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EPO-assisted TF (EPOTF) filtration using micro-ultrafiltration SiNx membrane filters isolated large quantities of bovine milk exosomes without deformation and clogging of membrane filters. The method yields high-purity intact exosomes suitable for various applications.

Isolation of Bovine Milk Exosome using Electrophoretic Oscillation Assisted Tangential Flow Filtration with Antifouling of Micro-ultrafiltration Membrane Filters,

Minji Ko, Hyeng Jin Kim, Jaeeun Park, Hansol Lee, Keyong Nam Lee, Kayoung Kim, Jaehyuk Lee, Seok Jeong Yoon, Tony Kim, Sekyoo Jeong, Kyun Heo, Youngkwang Lee, and Young Rag Do*

ACS Appl. Mater. Interfaces, 15, 26069–26080 (2023).

Volume 15, Issue 21, May 31, 2023